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Bioassay of butylated hydroxytoluene (BHT) for possible carcinogenicity. by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

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Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English


  • Carcinogens.,
  • Antioxidants -- Toxicology.,
  • Food preservatives -- Toxicology.

Book details:

Edition Notes

SeriesCarcinogenesis technical report series ; no. 150, DHEW publication ; no. (NIH) 79-1706, DHEW publication -- no. (NIH) 79-1706.
The Physical Object
Paginationix, 114 p. :
Number of Pages114
ID Numbers
Open LibraryOL15229824M

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Bioassay of butylated hydroxytoluene (BHT) for possible carcinogenicity. National Toxicology Program. A bioassay of BHT for possible carcinogenicity was conducted by administering the test chemical in feed to F rats and B6C3F1 mice. Groups of 50 rats and 50 mice of each sex were administered BHT at one of two doses, either 3, or 6, ppm. Online book: Additional Physical Format: Print version: Bioassay of butylated hydroxytoluene (BHT) for possible carcinogenicity (OCoLC) Material Type: Document, Government publication, National government publication, Internet resource: Document Type: Internet Resource, Computer File: All Authors / Contributors: Frederick Cancer.   The objective was to evaluate the preservative potential of rutin in combination with butylated hydroxytoluene (BHT) in cheese. Cheddar cheese was prepared with various combinations of rutin (10–60 ppm) and BHT (60– ppm) along with positive ( ppm BHT) and a negative : Bakhtawar Naseer, Sanaullah Iqbal, Namrah Waheed, Haroon Jamshaid, Muhammad Nadeem, Muhammad Nawaz.   Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) are phenolic antioxidants that are ubiquitous food additives found in foods containing fats or oils, as well as cosmetics and drugs. They continue to have provisional status on the GRAS list due to animal toxicology studies in animals. Usage appears to be increasing.

  Cancer Inst., 51 () 16 Y. Maeura and G.M. Williams, Enhancing effect of butylated hydroxytoluene on the development of liver altered foci and neoplasms induced by Nfluorenylacetamine in rats. Food Chem. Toxicol., 22 () 17 National Institute of Health Bioassay of Butylated Hydroxytoluene (BHT) for Possi- ble Carcinogenicity. Butylated Hydroxytoluene is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6. Butylated hydroxytoluene (BHT) inhibits autoxidation of unsaturated organic compounds. BHT is used in food, cosmetics and industrial fluids to prevent oxidation and free radical formation. Butylated hydroxytoluene (BHT), also known as dibutylhydroxytoluene, is a lipophilic organic compound, chemically a derivative of phenol, that is useful for its antioxidant properties. BHT is widely used to prevent free radical-mediated oxidation in fluids (e.g. fuels, oils) and other materials, and the regulations overseen by the U.S. F.D.A.—which considers BHT to be "generally recognized. The toxicology of antioxidants has become one of the more controversial areas in the continuing debate on the safety of food additives. In recent years, problems have arisen with the antioxidants butylated hydroxyanisole (BHA) & butylated hydroxytoluene (BHT) when new long-term studies showed that these compounds could produce tumours in animals.

Type in Butylated Hydroxytoluene and make sure you are searching on Libraries Worldwide. After your search results are brought up, look on the left-hand side. Click on "Book" and this will limit it to book. Unclick the thesis / ebook/ and microform boxes. Now you have a selection of about 60 books and government publications that mention BHT. Bioassay of Butylated Hydroxytoluene (BHT) for Possible Carcinogenicity (CASRN ) Rats: F/N; Mice: B6C3F1; Carcinogenesis Results. Male Rats Negative ; Female Rats Negative ; Male Mice Negative ; Female Mice Negative ; Dose: 0, , PPM/50 PER GROUP. Genetic Toxicology. In Vitro Cytogenetics (CA/SCE) () Completed. A single bioassay for antioxidants based on protection of tetrahymena pyriformis from the photodynamic toxicity of benz[a]pyrene. The effect of the antioxidants, butylated hydroxyanisole, butylated hydroxytoluene and propyl gallate on growth, liver and serum lipids . Immunologic Butylated hydroxytoluene in chewing gum should be considered as a possible cause of unexplained food allergy [24 A].. Butylated hydroxytoluene in chewing gum caused a disseminated urticarial eruption in a young woman. An adverse drug reaction was ruled out, and the only recent dietary change had been regular use of chewing gum containing butylated hydroxytoluene.